Resolve to Save Lives

In-Depth Science Review

Our in-depth science review is a snapshot of the new and emerging scientific evidence related to COVID-19.

Rendering of the 2019-nCoV virion. Dan Higgins, MAM/CDC/REUTERS


February 14, 2022

COVID-19 severity and vaccine effectiveness in the era of the Omicron variant.

February 14, 2022

COVID-19 severity and vaccine effectiveness in the era of the Omicron variant.

December 22, 2021

What do we know about the Novavax vaccine?

November 1, 2021

The glut of COVID-19 vaccines is a myth: How we can — and must — remove barriers to vaccinating the world against COVID-19

September 1, 2021

Update: Opening K-12 schools for in-person learning amidst vaccines and variants: what have we learned and how can this guide us?

August 20, 2021

Protecting the Immunocompromised: The Evidence for an Additional Dose of COVID-19 Vaccine
Research Highlights

August 2, 2021

A Hidden Toll: The Mental Health Impacts of COVID-19 on the Public Health Workforce
FAQ: Guillain Barre Syndrome and COVID-19 vaccines
Research Highlights

July 16, 2021

Opening K-12 schools for in-person learning amidst vaccines and variants: what have we learned and how can this guide us?
Myocarditis/Pericarditis FAQ
Research Highlights

June 4, 2021

In it for the Long Haul: More Questions than Answers on the Lasting Health Effects of COVID-19
FAQ: Did the COVID-19 vaccine work if you didn’t experience side effects?
Research Highlights

April 17 – May 13, 2021

COVID-19 in Africa: Are reported cases and deaths only the eyes of the hippo?
Research Highlights

March 18 – April 16, 2021

How genomic surveillance helps us understand SARS-CoV-2
FAQ: Should pregnant people get a COVID-19 vaccine?
Weekly Research Highlights

March 3 – 17, 2021

COVID-19 in Brazil: Developments, Warnings and Lessons
The COVID-19 epidemic in the State of Amazonas
Given the current state of the COVID-19 epidemic in Brazil, what can be done?
Weekly Research Highlights

February 22 – March 2, 2021

The latest on COVID-19 treatments: evidence, approvals, guidelines and the implications of new variants.
What do the data say about the new Johnson & Johnson COVID-19 vaccine?
Weekly Research Highlights

January 30 – February 17, 2021

In depth: Should second doses of COVID-19 vaccines be delayed?
Weekly Research Highlights

January 16 – 29, 2021

Should everyone wear medical masks to prevent the spread of COVID-19?
FAQ: What is the CDC doing to track SARS-CoV-2 variants
Weekly Research Highlights
New vaccine efficacy announcements

January 9 – 15, 2020

The utility and limitations of large-scale surveys during the COVID-19 pandemic
Weekly Research Highlights

December 19, 2020 – January 8, 2021

Early COVID-19 vaccination rollout top performers
Weekly Research Highlights

December 12 – 18, 2020

A national COVID-19 alert level framework
Restaurant dining and COVID-19
What is the Ellume COVID-19 Home Test, a new fully-at-home COVID-19 test?
Weekly Research Highlights

December 5 – 11, 2020

Immunity Passports
FAQ - What do the changes in the CDC’s quarantine recommendations mean for me?
Weekly Research Highlights

November 14 – December 4, 2020

Estimating the true number of COVID-19 cases and the case detection ratio in the United States
Excess mortality during the COVID-19 pandemic
Weekly Research Highlights

November 7 – 13, 2020

Tracking COVID-19 in the United States: Progress and Opportunities
Household transmission of COVID-19
What is vaccine efficacy?
Weekly Research Highlights

October 31 – November 6, 2020

Declining death rates among people severely ill with COVID-19
National COVID-19 websites
Weekly Research Highlights

October 10 – 30, 2020

COVID-19 and mass transit
Does reopening K-12 schools contribute to COVID-19 spread in communities?
What are monoclonal antibodies and antibody cocktail treatments for COVID-19?
Weekly Research Highlights

October 3 – 9, 2020

Mask mandate effectiveness
Weekly Research Highlights

September 26 – October 2, 2020

Dose (inoculum) of SARS-CoV-2 and COVID-19 severity
How is vaccine safety monitored in the U.S.?
Can dogs detect COVID-19?
Weekly Research Highlights

September 19 – 25, 2020

COVID-19 vaccine prioritization in the U.S.
COVID-19 vaccine prioritization on the global scale: the COVAX Facility
How can you be inside safely during cold weather?
Weekly Research Highlights

September 12 -18, 2020

Flu and COVID-19
COVID-19 and flu: Who gets infected and how?
General clinical features of flu and COVID-19
Severe flu and COVID-19
Comparing the severity of flu and COVID-19
Genetic structure and implications for acquired protective immunity and vaccines
Treating the flu and COVID-19
Weekly Research Highlights

August 29 – September 11, 2020

Emergency use authorization (EUA) of medical products during the COVID-19 pandemic including a look ahead at possible EUA of a COVID-19 vaccine
How do we track deaths from COVID-19?
Weekly Research Highlights

August 22 – 28, 2020

COVID-19 reinfection
Is it safe to fly during the COVID-19 pandemic?
What is convalescent plasma?
What is Abbott’s new 15-minute test for COVID-19?
Weekly Research Highlights

August 15 – 21, 2020

Update on COVID-19 in Africa
Herd immunity, reproduction numbers and human behavior during the COVID-19 pandemic
Guidance on how long people with COVID-19 should isolate
Heating, ventilation and air conditioning (HVAC) systems and managing indoor air during the COVID-19 pandemic
What is saliva-based testing for COVID-19?
Weekly Research Highlights

August 8 – 14, 2020

The indirect impacts of COVID-19 on health and essential health services in sub-Saharan Africa
Why focus on sub-Saharan Africa?
What did we learn from Ebola and can this be applied to COVID-19?
What are potential direct and indirect effects of COVID-19 on health and health systems?
How might COVID-19 affect health services?
How may the indirect health effects of COVID-19 be measured? What do the data show?
Weekly Research Highlights

August 1 – 7, 2020

The role of T cells in adaptive immunity to COVID-19
Seasonal influenza during the COVID-19 pandemic
Weekly Research Highlights

July 25 – 31, 2020

In-Depth Review of the 3 W’s: Wear a mask, Wash your hands, and Watch your distance.
Should the general public wear eye protection to protect from COVID-19?
Weekly Research Highlights

July 18 – 24, 2020

Update on COVID-19 vaccine development
What is antigen testing?
What is pooled testing?
Weekly Research Highlights

July 11 – 17, 2020

Tracking COVID-19 in the United States
Weekly Research Highlights

July 4 – 10, 2020

Update on airborne transmission of COVID-19: evidence and implications for precautions
Expanding social networks safely through bubbles
Weekly Research Highlights

June 27 – July 3, 2020

HIV and COVID-19
Colleges and universities confront COVID-19
Weekly Research Highlights

June 20 – 26, 2020

Reopening schools during the COVID-19 pandemic
Susceptibility, severity of illness and transmission of COVID-19 in children
Susceptibility of children to COVID-19
Severity of COVID-19 infection in children
COVID-19 transmission by children to others
The role of school closure in controlling COVID-19 transmission
Potential impacts of school closures due to COVID-19 and how to reopen schools safely
Weekly Research Highlights

June 13 – 19, 2020

COVID-19 trends in the United States
Face mask update
Fecal transmission of COVID-19
Dexamethasone use in those with severe COVID-19 illness
Weekly Research Highlights

June 6 – 12, 2020

MMR vaccine and COVID-19
ABO blood type and COVID-19
Where did SARS-CoV-2 come from?
What do we know about smoking, vaping and COVID-19?
What is a preprint article?
Weekly Research Highlights

May 30 – June 5, 2020

Eleven epidemiological fallacies in COVID-19
Returning to work and COVID-19
The impacts of COVID-19 on mental health in the United States
Addiction and recovery during COVID-19
Weekly Research Highlights

May 23 – 29, 2020

Testing and test data, what it can and cannot tell us
The influence of physical distancing on diseases other than COVID-19
Indoor versus outdoor transmission of COVID-19
Weekly Article Highlights

May 16 – 22, 2020

Asymptomatic infections in COVID-19 revisited
Anosmia revisited
Weekly Research Highlights

May 10 – 17, 2020

Estimated impact of COVID-19 on life expectancy in New York City
COVID-19 and surface contamination
The changing landscape of COVID-19 diagnostics
COVID-19 immunity certificates
Weekly Research Highlights

May 2 – 8, 2020

Assessing COVID-19 resurgence
Children and transmission risk
Hyperinflammatory shock and Kawasaki Disease with a link to COVID-19 in children
ACE inhibitors or angiotensin receptor blockers (ARBs) and risk for severe COVID-19 disease
What are COVID toes?
Public Health

April 25 – May 1, 2020

Country preparedness and COVID-19
Stroke, thrombotic, and thromboembolic events in COVID-19 patients
COVID-19 in correctional facilities and homeless shelters
Relaxing public health and social measures in the United States
Clinical Features

April 18 – 24, 2020

Past, current and future COVID-19 infections: the size of the iceberg and what tests can and can’t tell us
COVID-19 testing prioritization in the United States
Tracking the virus, its genome, and mutations - a critical aspect of disease surveillance.
COVID-19 and Noncommunicable Diseases
Other infectious diseases and COVID-19
Can I wear contact lenses during the COVID-19 pandemic?
Clinical features

April 11 – 17, 2020

Using data to assess adherence with public health and social measures can better inform decision-making
SARS-CoV-1 (SARS) vaccines and implications for SARS-CoV-2 (COVID-19) vaccine development
Hydroxychloroquine and potential impacts
Red eyes and COVID-19
Proximity to runners and cyclers
Clinical features

April 4 – 10, 2020

Nowcasting in the context of COVID-19
BCG and COVID-19
Impact of dosage (inoculum) on COVID-19 severity
Clinical features
How much do we touch our faces and what does that mean for COVID-19?
Sanitary recommendations for bringing packages into the home

March 28 – April 3, 2020

Syndromic surveillance should be explored as an early signal for COVID-19
Face masks in the community
Pets and COVID-19
How common is asymptomatic infection?
Can someone get re-infected?
How does COVID-19 relate to blood type?

March 21 – 27, 2020

Loss of smell or taste in COVID-19
Hydroxychloroquine for COVID-19 prophylaxis
Non-pharmaceutical interventions
Will a rise in outdoor temperature affect COVID-19?

March 14 – 20, 2020

COVID-19 Mortality by age
Antivirals for COVID-19
Pediatric COVID-19
Weekly research highlights
Should COVID-19 patients avoid NSAIDs (like ibuprofen)?
Does smoking increase the risk of infection from COVID-19?
Should anti-hypertensive medications in the Renin-Angiotensin System inhibition class be avoided because of the risk of COVID-19?

Covid-19 Resource Library

Explore high-quality resources and tools for COVID-19

Covid-19 In the Press

Press Releases and Resolve to Save Lives experts in the press